Cell line name NCC-MPNST1-C1
Synonyms NCCMPNST1C1
Accession CVCL_YU12
Resource Identification Initiative To cite this cell line use: NCC-MPNST1-C1 (RRID:CVCL_YU12)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia – CCLE).
Part of: NCC sarcoma cell line panel.
Population: Japanese.
Doubling time: 28 hours (PubMed=32099531).
Sequence variations
Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=32099531).
Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (PubMed=32099531).
Gene deletion; HGNC; 12362; TSC1; Zygosity=Homozygous (PubMed=32099531).
Mutation; HGNC; 1101; BRCA2; Simple; p.Lys1872Ter (c.5614A>T); ClinVar=VCV000037979; Zygosity=Heterozygous (PubMed=32099531).
Disease Malignant peripheral nerve sheath tumor (NCIt: C3798)
Neurofibromatosis type 1 (NCIt: C3273)
Malignant peripheral nerve sheath tumor (ORDO: Orphanet_3148)
Neurofibromatosis type 1 (ORDO: Orphanet_636)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 37Y
Category Cancer cell line
STR profile

Source(s): PubMed=32099531


Amelogenin X
D5S818 7,13
D7S820 10.3,11
D13S317 11,12
D16S539 10,11
D21S11 30,31
TH01 6
vWA 17,18

PubMed=32099531; DOI=10.1186/s12935-020-1128-z
Oyama R., Kito F., Takahashi M., Hattori E., Noguchi R., Takai Y., Sakumoto M., Qiao Z., Toki S., Sugawara M., Tanzawa Y., Kobayashi E., Nakatani F., Iwata S., Yoshida A., Kawai A., Kondo T.
Establishment and characterization of patient-derived cancer models of malignant peripheral nerve sheath tumors.
Cancer Cell Int. 20:58.1-58.15(2020)

Cell line databases/resources cancercelllines; CVCL_YU12
DepMap; ACH-002799
Encyclopedic resources Wikidata; Q95992534

Additional information

User Category

Academia/non-profit organization, For-profit organization


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