Cell line name NCC-UPS4-C1
Accession CVCL_B6KI
Resource Identification Initiative To cite this cell line use: NCC-UPS4-C1 (RRID:CVCL_B6KI)
Comments Part of: NCC sarcoma cell line panel.
Population: Japanese.
Doubling time: 76 hours (PubMed=35118583).
Omics: SNP array analysis.
Derived from site: Metastatic; Right knee, hypodermis; UBERON=UBERON_0001465+UBERON_0002072.
Sequence variations
Mutation; HGNC; 11998; TP53; Simple; p.Glu286Lys (c.856G>A); ClinVar=VCV000183752; Zygosity=Heterozygous (PubMed=35118583).
Mutation; HGNC; 11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Heterozygous (PubMed=35118583).
Disease Li-Fraumeni syndrome (NCIt: C3476)
Undifferentiated pleomorphic sarcoma (NCIt: C4247)
Li-Fraumeni syndrome (ORDO: Orphanet_524)
Undifferentiated pleomorphic sarcoma (ORDO: Orphanet_2023)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 32Y
Category Cancer cell line
STR profile

Source(s): PubMed=35118583


Amelogenin X
CSF1PO 11,12
D5S818 10,11
D7S820 11
D13S317 9,13
D16S539 12
D21S11 29,32.2
TH01 7,8
TPOX 8,9
vWA 14,19

PubMed=35118583; DOI=10.1007/s13577-022-00671-y
Ono T., Yoshimatsu Y., Noguchi R., Sin Y., Tsuchiya R., Akiyama T., Sugaya J., Fukushima S., Kojima N., Yoshida A., Kawai A., Kondo T.
Establishment and characterization of NCC-UPS4-C1: a novel cell line of undifferentiated pleomorphic sarcoma from a patient with Li-Fraumeni syndrome.
Hum. Cell 35:756-766(2022)

Cell line databases/resources cancercelllines; CVCL_B6KI
Encyclopedic resources Wikidata; Q112129416

Additional information

User Category

Academia/non-profit organization, For-profit organization


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