Cell line name NCC-OS1-X2-C1
Synonyms NCC-OS1-C1; NCCOS1X2C1
Accession CVCL_VM08
Resource Identification Initiative To cite this cell line use: NCC-OS1-X2-C1 (RRID:CVCL_VM08)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line      Encyclopedia – CCLE).
Part of: NCC sarcoma cell line panel.
Population: Japanese.
Characteristics: Established from a second generation xenograft established by      subcutaneous injection in female SCID mice.
Doubling time: 29 hours (PubMed=29943355).
Omics: Deep proteome analysis.
Derived from site: In situ; Bone, distal femur; UBERON=UBERON_0004406.
Sequence variations
Mutation; HGNC; 1787; CDKN2A; Simple; p.His66Arg (c.197A>G) (p.Pro80Pro, c.240A>G);      ClinVar=VCV000246117; Zygosity=Unspecified (DOI=10.2198/jelectroph.65.1).
Disease   Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
STR profile

    Source(s): PubMed=29943355


Amelogenin X
D5S818 12
D7S820 10,11
D13S317 8,10
D16S539 11
D21S11 30
TH01 9
TPOX 8,11
vWA 16,18

PubMed=29943355; DOI=10.1007/s11626-018-0274-2
Kito F., Oyama R., Sakumoto M., Takahashi M., Shiozawa K., Qiao Z., Sakamoto H., Hirose T., Setsu N., Yoshida A., Kawai A., Kondo T.
Establishment and characterization of novel patient-derived osteosarcoma xenograft and cell line.
In Vitro Cell. Dev. Biol. Anim. 54:528-536(2018)

Noguchi R., Yoshimatsu Y., Ono T., Sei A., Kondo T.
Proteogenomic approach to drug targets in osteosarcomas with different original sites.
J. Electroph. 65:1-11(2021)

Cell line databases/resources cancercelllines; CVCL_VM08
DepMap; ACH-002778
Encyclopedic resources Wikidata; Q95992540

Additional information

Weight N/A
User Category

Academia/non-profit organization, For-profit organization


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